Publications Citing the use of Strex Cell Stretching Systems and chambers

Uniaxial and static stretch dependent-signal transduction

Modeling human somite development and fibrodysplasia ossificans progressiva with induced pluripotent stem cells.
Nakajima, T., Shibata, M., Nishio, M., Nagata, S., Alev, C., Sakurai, H., … & Ikeya, M.
(2018). Development, 145(16), dev165431.

Localization of leucine-rich repeat-containing G-protein-coupled receptor 5-and Ki67-positive periodontal cells expressing runt-related transcription factor 2 during tooth movement.
Hosomichi, J., Shibutani, N., Yamaguchi, H., Hatano, K., Kuma, Y., Suzuki, T., … & Ono, T.
(2018). Orthodontic Waves.

Effects of Daidzein on the Production of Type I Collagen and Matrix Metalloproteinase1 by Stretched Human Periodontal Ligament Cells.
Yamaguchi, M., Nakayama, E., Shimizu, M., Kikuta, J., Horihata, S., & Kasai, K.
(2018) International Journal of Oral-Medical Sciences, 17(1), 27-32.

Cyclic Stretching Exacerbates Tendinitis by Enhancing NLRP3 Inflammasome Activity via F-Actin Depolymerization.
Chen, Q., Zhou, J., Zhang, B., Chen, Z., Luo, Q., & Song, G.
(2018). Inflammation, 1-13.

Hypoxia Triggers SENP1 (Sentrin-Specific Protease 1) Modulation of KLF15 (Kruppel-Like Factor 15) and Transcriptional Regulation of Arg2 (Arginase 2) in Pulmonary Endothelium.
Pandey, D., Nomura, Y., Rossberg, M. C., Hori, D., Bhatta, A., Keceli, G., … & Romer, L.
Arteriosclerosis, thrombosis, and vascular biology, ATVBAHA-117.

Contribution of plasma membrane lipid domains to red blood cell (re) shaping.
Léonard, C., Conrard, L., Guthmann, M., Pollet, H., Carquin, M., Vermylen, C., … & Tyteca, D.
(2017). Scientific reports, 7(1), 4264.

Inhibitory effect of JAK inhibitor on mechanical stress-induced protease expression by human articular chondrocytes.
Machida, T., Nishida, K., Nasu, Y., Nakahara, R., Ozawa, M., Harada, R., … & Ozaki, T.
(2017)
Inflammation Research, 1-11.

Real-time imaging of mechanically and chemically induced ATP release in human lung fibroblasts.
Takahashi, K., Ito, S., Furuya, K., Asano, S., Sokabe, M., & Hasegawa, Y.
(2017)
Respiratory Physiology & Neurobiology.

AB0072 Hyaluronan inhibition of mechanical stress-induced protease expressions by human chondrocytes.
M. Ozawa, K. Nishida, K. Hashizume, R. Nakahara, T. Saito, T. Kanazawa, R. Harada, T. Machida, T. Ozaki,
(2017).
Abstracts accepted for publication: Cartilage, synovium and osteoimmunology

Evaluation of Precise Optimal Cyclic Strain for Tenogenic Differentiation of MSCs.
Morita, Y., Sato, T., Watanabe, S., & Ju, Y.
(2016).  In Mechanics of Biological Systems and Materials, Volume 6 (pp. 149-155). Springer International Publishing.

Urothelial ATP exocytosis: regulation of bladder compliance in the urine storage phase.
Nakagomi, H., Yoshiyama, M., Mochizuki, T., Miyamoto, T., Komatsu, R., Imura, Y., … & Araki, I.
(2016). Scientific Reports, 6, 29761.

Bi-phasic activation of eNOS in response to uni-axial cyclic stretch is mediated by differential mechanisms in BAECs.
Takeda, H., Komori, K., Nishikimi, N., Nimura, Y., Sokabe, M., & Naruse, K.
(2006). Life sciences, 79(3), 233-239.

N-cadherin signals through Rac1 determine the localization of connexin 43 in cardiac myocytes.
Matsuda, T., Fujio, Y., Nariai, T., Ito, T., Yamane, M., Takatani, T., … & Azuma, J.
(2006). Journal of molecular and cellular cardiology, 40(4), 495-502

Stretch-induced cell proliferation is mediated by FAK-MAPK pathway.
Wang, J. G., Miyazu, M., Xiang, P., Li, S. N., Sokabe, M., & Naruse, K.
(2005). Life sciences, 76(24), 2817-2825.

Mechanotransduction by integrin is essential for IL-6 secretion from endothelial cells in response to uniaxial continuous stretch.
Sasamoto, A., Nagino, M., Kobayashi, S., Naruse, K., Nimura, Y., & Sokabe, M.
(2005).  American Journal of Physiology-Cell Physiology, 288(5), C1012-C1022.

Involvement of reactive oxygen species in cyclic stretch‐induced NF‐κB activation in human fibroblast cells.
Amma, H., Naruse, K., Ishiguro, N., & Sokabe, M.
(2005). British journal of pharmacology, 145(3), 364-373.

Characteristics of subepithelial fibroblasts as a mechano-sensor in the intestine: cell-shape-dependent ATP release and P2Y1 signaling.
Furuya, K., Sokabe, M., & Furuya, S.
(2005). Journal of cell science, 118(15), 3289-3304.

Uni-axial cyclic stretch induces the activation of transcription factor nuclear factor κB in human fibroblast cells.
Inoh, H., Ishiguro, N., Sawazaki, S. I., Amma, H., Miyazu, M., Iwata, H., … & Naruse, K.
(2002). The FASEB Journal, 16(3), 405-407.

Orientation change of cardiocytes induced by cyclic stretch stimulation: time dependency and involvement of protein kinases.
Kada, K., Yasui, K., Naruse, K., Kamiya, K., Kodama, I., & Toyama, J.
(1999). Journal of molecular and cellular cardiology, 31(1), 247-259.

Activation of pp60 (src) is critical for stretch-induced orienting response in fibroblasts.
Sai, X., Naruse, K., & Sokabe, M.
(1999). Journal of cell science, 112(9), 1365-1373.

Up-regulation of COX2 expression by uni-axial cyclic stretch in human lung fibroblast cells.
Kato, T., Ishiguro, N., Iwata, H., Kojima, T., Ito, T., & Naruse, K
(1998). Biochemical and biophysical research communications, 244(3), 615-619.

Pp125^ F^ A^ K is required for stretch dependent morphological response of endothelial cells.
Naruse, K., Yamada, T., Sai, X. R., Hamaguchi, M., & Sokabe, M.
(1998). Oncogene, 17(4), 455-463.

Cell adhesion

Poly (N-isopropylacrylamide) grafted PDMS substrate for controlling cell adhesion and detachment by dual stimulation of temperature and mechanical stress.
Akiyama, Y., Matsuyama, M., Yamato, M., Takeda, N., & Okano, T.
(2018). Biomacromolecules.

N-cadherin-mediated cell adhesion determines the plasticity for cell alignment in response to mechanical stretch in cultured cardiomyocytes.
Matsuda, T., Takahashi, K., Nariai, T., Ito, T., Takatani, T., Fujio, Y., & Azuma, J.
(2004). Biochemical and biophysical research communications, 326(1), 228-232.

SA channels

The time‐dependent variation of ATP release in mouse primary‐cultured urothelial cells is regulated by the clock gene.
Ihara, T., Mitsui, T., Nakamura, Y., Kanda, M., Tsuchiya, S., Kira, S., … & Shinozaki, Y.
(2018). in Neurourology and urodynamics.

Observation of Calcium Wave on Physical Stimulus for Realizing Cell Tactile Sensor.
Kawashima, H., Sajnani, U., Shimizu, M., & Hosoda, K.
(2018) Conference on Biomimetic and Biohybrid Systems (pp. 255-262). Springer, Cham.

The oscillation of intracellular Ca 2+ influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium.
Ihara, T., Mitsui, T., Nakamura, Y., Kanda, M., Tsuchiya, S., Kira, S., … & Shigetomi, E.
(2018) Scientific Reports, 8(1), 5699.

Leucine Supplementation After Mechanical Stimulation Activates Protein Synthesis via L‐type Amino Acid Transporter 1 In Vitro.
Nakai, N., Kawano, F., Murakami, T., Nakata, K., & Higashida, K.
(2017) Journal of Cellular Biochemistry.

P2Y 6-deficiency increases micturition frequency and attenuates sustained contractility of the urinary bladder in mice.
Kira, S., Yoshiyama, M., Tsuchiya, S., Shigetomi, E., Miyamoto, T., Nakagomi, H., … & Koizumi, S.,
(2017)
Scientific Reports, 7(1), 771.

Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle.
Ito, S., Kume, H., Oguma, T., Ito, Y., Kondo, M., Shimokata, K., … & Naruse, K.
(2006). European journal of pharmacology, 552(1), 135-142.

Calcium regulates the PI3K-Akt pathway in stretched osteoblasts.
Danciu, T. E., Adam, R. M., Naruse, K., Freeman, M. R., & Hauschka, P. V.
(2003).FEBS letters, 536(1), 193-197.

Involvement of SA channels in orienting response of cultured endothelial cells to cyclic stretch.
Naruse, K., Yamada, T., & Sokabe, M.
(1998). American Journal of Physiology-Heart and Circulatory Physiology, 274(5), H1532-H1538.

SA channel mediates superoxide production in HUVECs.
Aikawa, K., Nishikimi, N., Sakurai, T., Nimura, Y., Sokabe, M., & Naruse, K.
(2001). Life sciences, 69(15), 1717-1724.

Nano-materials
Fabrication of reconfigurable protein matrices by cracking.
Zhu, X., Mills, K. L., Peters, P. R., Bahng, J. H., Liu, E. H., Shim, J., … & Takayama, S.
(2005). Nature materials, 4(5), 403-406.
Mechanotransduction: References and Review Articles
Real-time imaging of mechanically and chemically induced ATP release in human lung fibroblasts.
Takahashi, K., Ito, S., Furuya, K., Asano, S., Sokabe, M., & Hasegawa, Y.
(2017)
Respiratory Physiology & Neurobiology.

P2Y 6-deficiency increases micturition frequency and attenuates sustained contractility of the urinary bladder in mice.
Kira, S., Yoshiyama, M., Tsuchiya, S., Shigetomi, E., Miyamoto, T., Nakagomi, H., … & Koizumi, S.,
(2017)
Scientific Reports, 7(1), 771.

Mechanotransduction research driving soft lithography. Naruse, K. (2006). Protein, Nucleic Acid and Enzyme, 51, 705-714

Activation of a mechanosensitive BK channel by membrane stress created with amphipaths. Qi, Z., Chi, S., Su, X., Naruse, K., & Sokabe, M. (2005). Molecular membrane biology, 22(6), 519-527.

Soft lithography and mechanobiology. Naruse, K.
(2004). Vascular Biology & Medicine, 5,237-244

Molecular identification of a eukaryotic, stretch-activated nonselective cation channel. Kanzaki, M., Nagasawa, M., Kojima, I., Sato, C., Naruse, K., Sokabe, M., & Iida, H. (1999). Science, 285(5429), 882-886.

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